AN ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH TANDEM MASS SPECTROMETRY METHOD FOR DETERMINATION OF 10 ALKALOIDS IN BEAGLE DOG PLASMA AFTER THE ORAL ADMINISTRATION OF THE CORYDALIS YANHUSUO W.T. WANG EXTRACT AND YUANHUZHITONG TABLETS

An Ultra-High Performance Liquid Chromatography with Tandem Mass Spectrometry Method for Determination of 10 Alkaloids in Beagle Dog Plasma after the Oral Administration of the Corydalis yanhusuo W.T. Wang Extract and Yuanhuzhitong Tablets

This study has developed a sensitive and simple ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry method for the simultaneous determination of corydaline, dehydrocorydaline, tetrahydropalmatine, protopine, palmatine, tetrahydroberberine, columbamine, berberine, coptisine and berberrubine in beagle dog pla

read more

Incubation and intuition in creative problem solving.

Creative problem solving, in which novel solutions are required, has often been seen as involving a special role for unconscious processes (Unconscious Work) which can lead to sudden intuitive solutions (insights) when a problem is set aside during incubation periods.This notion of Unconscious Work during Men Skin Care incubation periods is support

read more

Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas

The purpose: to establish influence of a full ischemia of different duration and the subsequent reperfusionon pathology development in pancreas of rats by means of laser speckle-visualization and lifetime digital microscopy.Materials and Methods.The Feminine Cleansing work has been performed on 42 white rats of line Wistar in weight of 200-250 Rese

read more

DISC-3D: dual-hydrogel system enhances optical imaging and enables correlative mass spectrometry imaging of invading multicellular tumor spheroids

Abstract Multicellular tumor spheroids embedded in collagen I matrices are common in vitro systems for the study of solid tumors that reflect the physiological environment and complexities of the in vivo environment.While collagen I environments are physiologically relevant and permissive of cell invasion, studying spheroids in such hydrogels prese

read more